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2-(3-hydroxy-2-quinolyl)-5-phenyl-1H-indene-1,3(2H)-dione
- Name 2-(3-hydroxy-2-quinolyl)-5-phenyl-1H-indene-1,3(2H)-dione
- CAS 34432-91-2
- Purity 99%
Product Details
Cost-effective and customizable 2-(3-hydroxy-2-quinolyl)-5-phenyl-1H-indene-1,3(2H)-dione 34432-91-2 in stock
- Molecular Formula: C24H15 N O3
- Molecular Weight: 365.3808
- Vapor Pressure: 1.28E-15mmHg at 25°C
- Boiling Point: 613°Cat760mmHg
- Flash Point: 324.5°C
- PSA： 67.26000
- Density: 1.369g/cm3
- LogP: 4.77020
2-(3-hydroxy-2-quinolyl)-5-phenyl-1H-indene-1,3(2H)-dione(Cas 34432-91-2) Usage
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General Description |
The chemical 2-(3-hydroxy-2-quinolyl)-5-phenyl-1H-indene-1,3(2H)-dione, also known as HIQ-PhOH, is a heterocyclic compound with potential anti-tumor properties. It is a synthetic analogue of the natural compound camptothecin, which exhibits strong anti-cancer activity. HIQ-PhOH has been investigated for its ability to inhibit the growth of cancer cells by targeting topoisomerase I, an enzyme that is critical for DNA replication and repair. Research has shown that 2-(3-hydroxy-2-quinolyl)-5-phenyl-1H-indene-1,3(2H)-dione can induce cell death in various cancer cell types, making it a promising candidate for further development as a potential anti-cancer drug. |
InChI:InChI=1/C24H15NO3/c26-20-13-16-8-4-5-9-19(16)25-22(20)21-23(27)17-11-10-15(12-18(17)24(21)28)14-6-2-1-3-7-14/h1-13,21,26H
